Dr. Keen's Blog

Can a drug to treat diabetes and a drug to treat hypertension be an effective anti-cancer combination?

Data is preliminary and still being tested in mouse models, but a recent paper in Science Advances details that combining a diabetes drug, metformin, with an anti-hyptertensive, syrosingopine, may work to prevent cancer cell growth. The December publication by Don Benjamin and colleagues shows how these two common drugs may interact. Metformin is a common diabetes drug that has been shown to have anti-cancer properties. (see Evans, Libby, Jiralerspong, DeCensi, and Noto. It is... Read More

Combination cancer therapy

There is so much talk about immunotherapy these days. Sidney Kimmel and Michael Bloomberg just donated money to establish the Bloomberg-Kimmel Institute for Cancer Immunotherapy at Johns Hopkins University. The Institute of Medicine discussed what policies should be considered with this new emerging treatment paradigm. New ideas about how to combine immunotherapy with other cancer therapies are emerging almost daily. After many years of intense research into how the immune... Read More

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